Results Of Kidney Transplantation In HIV-Infected Patients

Results Of Kidney Transplantation In HIV-Infected Patients.
A large, different turn over provides more evidence that people infected with HIV, the virus that causes AIDS, do almost as well on the survival vanguard as other patients when they undergo kidney transplants. Up until the mid-1990s, physicians tended to dodge giving kidney transplants to HIV patients because of fear that AIDS would quickly kill them. Since then, altered medications have greatly lengthened life spans for HIV patients, and surgeons routinely pull off kidney transplants on them in some urban hospitals.

The study authors, led by Dr Peter G Stock, a professor of surgery at the University of California, San Francisco, examined the medical records of 150 HIV-infected patients who underwent kidney transplantation between 2003 and 2009. They surface their findings in the Nov. 18 affair of the New England Journal of Medicine.

The researchers found that about 95 percent of the transfer patients lived for one year and about 88 percent lived for three years. Those survival rates decrease between those for kidney move patients in habitual and those who are aged 65 and over. "They live just as long as the other patients we consider for transplantation. They're essentially the same as the hit the sack of our patients," said transplant specialist Dr Silas P Norman, an second professor of internal medicine at the University of Michigan. Norman was not part of the contemplation team.

There was one troubling finding: the bodies of HIV patients were more likely to reject the kidneys than the bodies of other resettle patients. It's likely that surgeons will need to better tailor their procedures to help preclude organ rejection, said transplant surgeon Dr Dorry Segev. This should happen as surgeons glean more experience with transplants in HIV patients an associate professor of surgery and epidemiology at Johns Hopkins Medical Institutions, who was insolent with the study findings.

Overall "treatment of HIV-infected patients undergoing kidney transplantation is positively not straightforward, and this study has identified some challenges for the transplant community to address". On the sharp-witted side, transplant procedures didn't appear to have much of an impact on the HIV infections in the patients.

In years days of yore transplant surgeons worried about how the AIDS virus would interact with the medications given to displace patients that are designed to dampen the immune system. The concern was that "these patients are now doing well, and you're accepted to give them medicine and undo all their benefits".

But it turns out that transplantation drugs have the opposite capacity and often suppress the AIDS virus. This is because HIV revs up the immune system while the drugs transform it down. Norman said he expects that the new findings will encourage more surgeons to perform kidney transplants on HIV patients, who are c oftentimes surviving long enough to develop diseases that typically aim older people. "There are still a lot of people in the community, including transplant professionals, nephrologists and transmissible disease professionals, who still don't appreciate that many of these patients are good prospects for transplantation how stars grow it. They don't admire how many procedures have been done to date, and how we're getting overall very good outcomes".