Alzheimer's Disease Against A Cancer

Alzheimer's Disease Against A Cancer.
Although a observe in 2012 suggested a cancer medication could reverse the thinking and memory problems associated with Alzheimer's disease, three groups of researchers now assert they have been unable to duplicate those findings. The teams said their scrutiny could have serious implications for patient safety since the drug involved in the study, bexarotene (Targretin), has grim side effects, such as major blood-lipid abnormalities, pancreatitis, headaches, fatigue, weight gain, depression, nausea, vomiting, constipation and rash proextenderusa com. "Anecdotally, we have all heard that physicians are treating their Alzheimer's patients with bexarotene, a cancer medicate with hard side effects," said study co-author Robert Vassar, a professor of apartment and molecular biology at Northwestern University Feinberg School of Medicine, in Chicago.

This profession should be ended immediately, given the failure of three independent research groups to replicate the plaque-lowering things of bexarotene. The US Food and Drug Administration approved bexarotene in 1999 to act toward refractory cutaneous T-cell lymphoma proextender ciudad acuГ±a price. Once approved, however, the antidepressant also was available by prescription for "off-label" uses.

The 2012 study suggested that bexarotene was able to right away reverse the build-up of beta amyloid plaques in the brains of mice. The authors of the opening study concluded that treatment with the drug might reverse the cognitive and memory problems associated with the incident of Alzheimer's. Sangram Sisodia, a professor of neurosciences at the University of Chicago and a study co-author of the modern development research, admitted being skeptical about the initial findings.