The Flu Vaccine Is Little Effect On Men.
The flu vaccine is less in operation for men than women, and researchers at Stanford University hold they've figured out why. The man's hormone testosterone causes genes in the immune way to produce fewer antibodies, or defense mechanisms, in response to the vaccine, they found extenderdlx.com. "Men, typically, do worse than women in protected response to infection and vaccination," said Stanford research mate David Furman, the lead study investigator.
For instance, men are more susceptible to bacterial, viral, fungal and parasitic infection than women. And men's untouched systems don't come back as robustly as women's to vaccinations against flu, yellow fever, measles, hepatitis and many other diseases source. For the study, published online Dec 23, 2013 in the Proceedings of the National Academy of Sciences, the researchers analyzed the blood of nearly 90 adults after they received a seasonal flu shot.
Men with the highest testosterone levels had the worst answer to the flu vaccine across the board. Testosterone is tied to standard manful reproductive characteristics, such as muscle strength, beard growth and risk-taking. "We found a set of genes in men that when activated caused a lousy response to the vaccine, but were not involved in female response. Some of these genes are regulated by testosterone".
It's testosterone's obtain on these genes that causes the poor vaccine response. "This has a lot of implications for vaccine development". Vaccine reaction might be better if men were given twice the dose, he suggested, or possibly if testosterone levels were reduced. The whole picture isn't quite clear or simple. Men's weaker response to the flu vaccine is only seen for some strains of flu.
Showing posts with label response. Show all posts
Showing posts with label response. Show all posts
Wednesday 30 January 2019
Tuesday 8 May 2018
Increased Weight Reduces The Brain's Response To Tasty Food
Increased Weight Reduces The Brain's Response To Tasty Food.
Most clan unquestionably find drinking a milkshake a pleasurable experience, sometimes well so desi malu anti. But apparently that's less apt to be the case among those who are overweight or obese.
Overeating, it seems, dims the neurological comeback to the consumption of yummy foods such as milkshakes, a new study suggests hanzal ointment natural m age. That answer is generated in the caudate nucleus of the brain, a region involved with reward.
Researchers using running magnetic resonance imaging (fMRI) found that that overweight and obese people showed less activity in this brain sphere when drinking a milkshake than did normal-weight people.
"The higher your BMI [body mass index], the trim your caudate response when you eat a milkshake," said study lead author Dana Small, an affiliated professor of psychiatry at Yale and an associate fellow at the university's John B. Pierce Laboratory.
The outcome was especially strong in adults who had a particular variant of the taqIA A1 gene, which has been linked to a heightened gamble of obesity. In them the decreased brain response to the milkshake was very pronounced. About a third of Americans have the variant.
The findings were to have been presented earlier this week at an American College of Neuropsychopharmacology union in Miami.
Just what this says about why ancestors overeat or why dieters say it's so hard to reject highly rewarding foods is not entirely clear. But the researchers have some theories.
When asked how pleasant they found the milkshake, overweight and obese participants in the study responded in ways that did not differ much from those of normal-weight participants, suggesting that the vindication is not that obese people don't enjoy milkshakes any more or less.
And when they did brain scans in children at peril for obesity because both parents were obese, the researchers found the opposite of what they found in overweight adults.
Children at jeopardy of obesity actually had an increased caudate response to milkshake consumption, compared with kids not considered at endanger for obesity because they had lean parents.
What that suggests, the researchers said, is that the caudate response decreases as a conclusion of overeating through the lifespan.
"The decrease in caudate response doesn't precede weight gain, it follows it. That suggests the decreased caudate feedback is a consequence, rather than a cause, of overeating."
Studies in rats have had nearly the same results, said Paul Kenny, an associate professor in the behavioral and molecular neuroscience lab at the Scripps Research Institute in Jupiter, Fla.
Most clan unquestionably find drinking a milkshake a pleasurable experience, sometimes well so desi malu anti. But apparently that's less apt to be the case among those who are overweight or obese.
Overeating, it seems, dims the neurological comeback to the consumption of yummy foods such as milkshakes, a new study suggests hanzal ointment natural m age. That answer is generated in the caudate nucleus of the brain, a region involved with reward.
Researchers using running magnetic resonance imaging (fMRI) found that that overweight and obese people showed less activity in this brain sphere when drinking a milkshake than did normal-weight people.
"The higher your BMI [body mass index], the trim your caudate response when you eat a milkshake," said study lead author Dana Small, an affiliated professor of psychiatry at Yale and an associate fellow at the university's John B. Pierce Laboratory.
The outcome was especially strong in adults who had a particular variant of the taqIA A1 gene, which has been linked to a heightened gamble of obesity. In them the decreased brain response to the milkshake was very pronounced. About a third of Americans have the variant.
The findings were to have been presented earlier this week at an American College of Neuropsychopharmacology union in Miami.
Just what this says about why ancestors overeat or why dieters say it's so hard to reject highly rewarding foods is not entirely clear. But the researchers have some theories.
When asked how pleasant they found the milkshake, overweight and obese participants in the study responded in ways that did not differ much from those of normal-weight participants, suggesting that the vindication is not that obese people don't enjoy milkshakes any more or less.
And when they did brain scans in children at peril for obesity because both parents were obese, the researchers found the opposite of what they found in overweight adults.
Children at jeopardy of obesity actually had an increased caudate response to milkshake consumption, compared with kids not considered at endanger for obesity because they had lean parents.
What that suggests, the researchers said, is that the caudate response decreases as a conclusion of overeating through the lifespan.
"The decrease in caudate response doesn't precede weight gain, it follows it. That suggests the decreased caudate feedback is a consequence, rather than a cause, of overeating."
Studies in rats have had nearly the same results, said Paul Kenny, an associate professor in the behavioral and molecular neuroscience lab at the Scripps Research Institute in Jupiter, Fla.
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