A Blood Transfusion And Coronary Artery Bypass Surgery.
Receiving a blood transfusion during courage route surgery may raise a patient's risk of pneumonia, researchers report. "The know-how to store and transfuse blood is one of medicine's greatest accomplishments, but we are continuing to woo that receiving a blood transfusion may alter a patient's ability to fight infection," Dr James Edgerton, of The Heart Hospital, Baylor Plano in Texas, said in a Society of Thoracic Surgeons low-down release. He was not interested in the study helpful hints. For the current study, investigators looked at observations on more than 16000 patients who had heart bypass surgery.
The surgeries took burden at 33 US hospitals between 2011 and 2013. Nearly 40 percent of those surgical patients received red blood stall transfusions, the findings showed. Just under 4 percent of the unrestricted group developed pneumonia. People given one or two units of red blood cells were twice as inclined to to develop pneumonia compared to those who didn't receive blood transfusions read this. Those who received six units or more were 14 times more indubitably to develop pneumonia, the researchers found.
Showing posts with label transfusions. Show all posts
Showing posts with label transfusions. Show all posts
Friday 26 April 2019
Sunday 21 August 2016
Doctors Do A Blood Transfusion For The Involvement Of Patients In Trials Of New Cancer Drugs
Doctors Do A Blood Transfusion For The Involvement Of Patients In Trials Of New Cancer Drugs.
Canadian researchers aver they've noticed a distressing trend: Cancer doctors ordering supererogatory blood transfusions so that critically ill patients can qualify for drug trials. In a letter published recently in the New England Journal of Medicine, the researchers article on three cases during the last year in Toronto hospitals in which physicians ordered blood transfusions that could fetch the patients appear healthier for the solitary purpose of getting them into clinical trials for chemotherapy drugs. The practice raises both medical and virtuous concerns, the authors say.
And "On the physician side, you want to do the best for your patients," said co-author Dr Jeannie Callum, top dog of transfusion medicine and tissue banks at Sunnybrook Health Sciences Centre in Toronto. "If these patients have no other options hand to them, you want to do everything you can to get them into a clinical trial. But the submissive is put in a horrible position, which is, 'If you want in to the trial, you have to have the transfusion.' But the transfusion only carries risks to them".
A surprisingly serious complication of blood transfusions is transfusion-related pointed lung injury, which occurs in about one in 5000 transfusions and usually requires the patient to go on life support, said Callum. But in addition to the potential for physical harm, enrolling very sick persons in a clinical trial can also skew the study's results - making the drug perform worse than it might in patients whose sickness was not as far along.
The unnecessary transfusions were discovered by the Toronto Transfusion Collaboration, a consortium of six urban area hospitals formed to carefully review all transfusions as a means of improving patient safety. At this point, it's inconceivable to know how often transfusions are ordered just to get patients into clinical trials. When she contacted colleagues around the period to find out if the practice is widespread, all replied that they didn't sift the reasons for ordering blood transfusions and so would have no way of knowing.
Canadian researchers aver they've noticed a distressing trend: Cancer doctors ordering supererogatory blood transfusions so that critically ill patients can qualify for drug trials. In a letter published recently in the New England Journal of Medicine, the researchers article on three cases during the last year in Toronto hospitals in which physicians ordered blood transfusions that could fetch the patients appear healthier for the solitary purpose of getting them into clinical trials for chemotherapy drugs. The practice raises both medical and virtuous concerns, the authors say.
And "On the physician side, you want to do the best for your patients," said co-author Dr Jeannie Callum, top dog of transfusion medicine and tissue banks at Sunnybrook Health Sciences Centre in Toronto. "If these patients have no other options hand to them, you want to do everything you can to get them into a clinical trial. But the submissive is put in a horrible position, which is, 'If you want in to the trial, you have to have the transfusion.' But the transfusion only carries risks to them".
A surprisingly serious complication of blood transfusions is transfusion-related pointed lung injury, which occurs in about one in 5000 transfusions and usually requires the patient to go on life support, said Callum. But in addition to the potential for physical harm, enrolling very sick persons in a clinical trial can also skew the study's results - making the drug perform worse than it might in patients whose sickness was not as far along.
The unnecessary transfusions were discovered by the Toronto Transfusion Collaboration, a consortium of six urban area hospitals formed to carefully review all transfusions as a means of improving patient safety. At this point, it's inconceivable to know how often transfusions are ordered just to get patients into clinical trials. When she contacted colleagues around the period to find out if the practice is widespread, all replied that they didn't sift the reasons for ordering blood transfusions and so would have no way of knowing.
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